HomeMedicine & BiophysicsHormesis Dose-Response Simulator

Hormesis Dose-Response Simulator

Interactive 3D simulator of toxicological hormesis: watch a population of organisms respond to a toxin as dose rises, tracing the biphasic (low-dose stimulation, high-dose inhibition) Brain-Cousens dose-response curve.

Medicine & Biophysics3DModerate60 FPS📱 Mobile-adapted⇄ 2D version
toxicology ↗ Open standalone

Toxicology's simple story — "more toxin, worse outcome" — breaks down at low doses for a documented class of stressors: hormesis, a biphasic response where a mild dose of a substance that is harmful at high concentration actually stimulates the organism, before the classic toxic decline takes over. This simulator renders the Brain–Cousens hormesis model as a live 3D dose-response curve alongside a grid of individual organisms, each with its own randomly drawn sensitivity, so you can watch a population's survival count rise slightly before collapsing as the toxin dose climbs. Adjust the hormetic strength, potency and ED50 threshold to see how the characteristic inverted-U hump forms, flattens, or disappears entirely into an ordinary monotonic toxicity curve.

⚙ Under the hood

Watch a population of organisms respond to a toxin across the full dose range and trace the biphasic Brain-Cousens hormesis curve, where low doses stimulate and high doses inhibit.

toxicologyhormesisdose-responsepharmacologyecotoxicology

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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