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💊 Cytochrome P450 Drug Metabolism Simulator

Explore how liver cytochrome P450 enzymes break down drugs over time, and how inhibitors or inducers reshape plasma concentration curves to trigger toxicity or treatment failure.

Medicine & Biophysics3DModerate60 FPS⚡ Plasma

The simulation shows a liver enzyme pool metabolizing a drug over time, then lets you introduce a competing molecule as an inhibitor or inducer to see how the plasma concentration curve shifts toward toxicity or subtherapeutic failure.

🔬 What It Demonstrates

🎮 How to Use

Adjust the drug dose slider and select an interacting molecule to add as an inhibitor or inducer, then watch the plasma concentration curve update in real time along with a toxicity and efficacy threshold overlay.

💡 Did You Know?

CYP3A4, a single enzyme isoform, is estimated to metabolize roughly half of all clinically prescribed medications in use today.

⚙ Under the hood

Explore how liver cytochrome P450 enzymes break down drugs over time, and how inhibitors or inducers reshape plasma concentration curves to trigger toxicity or treatment failure.

pharmacologycytochrome p450drug metabolismliver enzymesdrug interactionspharmacokineticstoxicologycyp3a4

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install