SPION MRI Contrast & T2* Darkening (2D)
2D Canvas lab: watch a top-down T2*-weighted MRI slice darken around a SPION nanoparticle cluster as concentration, core size, echo time and tissue baseline change the local dephasing field.
This 2D companion draws the same T2*-weighted MRI slice as the 3D version directly in Canvas2D — top-down, at full resolution, without a camera to orbit. A cluster of superparamagnetic iron-oxide nanoparticles (SPIONs) accumulates in a region of interest; each particle locally distorts the magnetic field, accelerating the dephasing of nearby water protons. The slice darkens around the cluster as echo time increases, with the dark "blooming" halo extending well beyond each particle's physical size. Tune nanoparticle concentration, iron-oxide core size, echo time and the surrounding tissue's own T2 baseline, or click the slice to re-seed the dose at a new location.
2D Canvas simulator of SPIONs as an MRI contrast agent: a top-down T2*-weighted slice darkens as nanoparticle concentration, core size, echo time and tissue baseline change the local dephasing field R2*local = R2_tissue + Σᵢ A(size) / (1 + (d / r_dephase)²).
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install