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Chromatin Remodeling Kymograph: Nucleosome Space-Time Map

2D space-time (kymograph) simulation of ATP-dependent chromatin remodeling: nucleosome positions along the DNA fiber are plotted as a scrolling position-vs-time raster, revealing SWI/SNF promoter-clearing and ISWI-style spacing as diagonal sliding trajectories.

Molecular Biology2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version

Details

CategoryMolecular Biology

RenderingCanvas 2D

DifficultyAdvanced

Target FPS60

ControlsToggle between spacing (ISWI-style) and promoter-clearing (SWI/SNF-style) remodeler modes, adjust the ATP turnover rate and the number of simultaneously active remodeler complexes with sliders, and reset the chromatin fiber to a fresh randomized layout — the scrolling kymograph below the instantaneous track records every resulting nucleosome trajectory over time.

chromatin remodelingnucleosomekymographSWI/SNFISWIepigeneticsspace-time diagram

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Nucleosomes are not fixed in place — ATP-powered chromatin remodeling complexes actively reposition them along the DNA fiber. This 2D companion sim plots the same coarse-grained sliding model as a kymograph: a scrolling position-vs-time raster where every nucleosome's history becomes a visible streak, so repositioning shows up directly as motion through time rather than as an instantaneous snapshot. Switch between an ISWI/CHD1-style "spacing" motor that senses linker DNA on each side of a nucleosome and equalizes it, and a SWI/SNF/RSC-style motor that clears a marked promoter window to open a nucleosome-depleted region, while live readouts track promoter accessibility, mean linker length and total ATP cycles consumed.

⚙ Under the hood

2D space-time (kymograph) companion to the 3D chromatin-remodeling simulator: nucleosome positions along the DNA fiber are plotted as a scrolling position-vs-time raster, so ATP-dependent SWI/SNF promoter-clearing and ISWI-style spacing show up directly as bending, colliding streaks instead of an instantaneous 3D snapshot.

chromatin remodelingnucleosomekymographSWI/SNFISWIepigeneticsspace-time diagram

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install