Home▸Medicine & Biophysics▸Skin Barrier: Lipid Mortar Integrity Lab

Skin Barrier: Lipid Mortar Integrity Lab

Interactive 3D model of the stratum corneum's brick-and-mortar structure: drag barrier integrity from intact to damaged and watch the lipid mortar between corneocytes visibly gap, water vapor escape faster (rising TEWL), and irritant particles punch through instead of being blocked.

Medicine & Biophysics3DModerate60 FPS💧 Water

Details

CategoryMedicine & Biophysics

RenderingThree.js · WebGL

DifficultyModerate

Target FPS60

ControlsBarrier integrity slider (0-100%) reshapes the lipid mortar seams between corneocyte bricks from sealed to gapped; Strip with soap / Repair barrier buttons jump integrity down/up by 30 points; drag to orbit and scroll to zoom the 3D cross-section; live readouts show barrier integrity %, TEWL rate and external-substance penetration rate as water and irritant particles animate through the structure.

Three.jsMedicineDermatologySkin BarrierStratum CorneumLipid MatrixTransepidermal Water LossBiophysics

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The stratum corneum blocks water loss and outside irritants at the same time, using one structure: flattened corneocyte "bricks" sealed together by a layered lipid "mortar." This model erodes that mortar as you drag barrier integrity down, so you can watch water escape faster (rising TEWL) and irritant particles start punching through the same widening gaps, live.

⚙ Under the hood

Interactive 3D cross-section of the stratum corneum's brick-and-mortar structure: drag the lipid mortar's integrity from intact to depleted and watch the seams between corneocyte bricks visibly gap open, water molecules escape upward faster (a live transepidermal water loss readout), and irritant/allergen particles switch from being blocked at the surface to punching straight through into deeper skin.

Three.jsMedicineDermatologySkin BarrierStratum CorneumLipid MatrixTransepidermal Water LossBiophysics

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install