Nerve Guidance Conduit: Axon Regrowth Across a Gap

This simulator models regenerating axon growth cones crossing a nerve guidance conduit bridging a peripheral nerve gap. Each growth cone follows a biased persistent random walk shaped by a chemotactic NGF gradient from the distal stump and contact guidance from the conduit's internal microchannels, reflecting off the lumen wall exactly as a real growth cone is confined by the conduit membrane. Adjust the chemotactic and contact-guidance strengths, extension rate, and lumen diameter to see how they trade off in the live bridging success rate, average bridging time, and lateral deviation — the same variables tissue engineers tune when designing conduit scaffolds.