HomeNeuroscience & BiophysicsVirtual Lesion Simulator 2D: Connectome Graph Lesion-Deficit Mapping

Virtual Lesion Simulator 2D: Connectome Graph Lesion-Deficit Mapping

Ablate regions of a schematic 14-node brain connectome drawn as a live 2D graph and watch Attention, Memory and Language task performance degrade in real time, computed from graph global efficiency over Floyd-Warshall shortest paths exactly as lesion-deficit neuropsychology models it.

Neuroscience & Biophysics2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version
2d-neuropsychology-simulations ↗ Open standalone

A "virtual lesion" is how computational neuropsychology studies brain damage without harming anyone: take a network model of interconnected brain regions, knock out or weaken a node, and measure how far the network's ability to route signal between task-relevant areas collapses. This 2D graph version builds the same schematic 14-region connectome as its 3D sibling — thalamic relay, fronto-parietal attention hubs, the hippocampal memory loop, and the Broca-Wernicke language pathway — but renders it as a pannable, zoomable node-link diagram so the exact Floyd-Warshall distances and global-efficiency math are always in view alongside a live distance-matrix heatmap and a severity-response curve. Lesion any region at any severity, tune the edge-dropout threshold and pulse hop budget, and watch Attention, Memory or Language performance degrade exactly as network-neuroscience models predict.

⚙ Under the hood

Ablate regions of a schematic 14-node brain connectome drawn as a live, pannable 2D graph and watch Attention, Memory and Language task performance degrade in real time, computed from graph global efficiency over Floyd-Warshall shortest paths exactly as lesion-deficit neuropsychology models it.

neuropsychologyconnectomebrain lesiongraph theorycognitive sciencenetwork neuroscience

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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