Pharmacogenomic Dosing Simulator

A patient's CYP450 enzyme genotype — poor, intermediate, normal, rapid or ultrarapid metabolizer — sets how fast their body clears a drug, and that single factor can shift the same milligram dose from safely therapeutic to dangerously toxic or uselessly sub-therapeutic in someone else. This simulator runs a real one-compartment pharmacokinetic model with first-order absorption: pick a genotype, set the dose and dosing interval, and watch the blood-concentration curve rise and fall with each repeated intake against a shaded therapeutic window. Adjust dose and interval genotype-by-genotype to see exactly how a prescriber compensates for fast or slow CYP450 clearance to keep a real patient safe and effective.