HomeMedicine & BiophysicsAgonist–Antagonist Dose-Response Simulator

Agonist–Antagonist Dose-Response Simulator

Interactive 3D receptor-binding simulator: titrate an agonist against a receptor field and watch a competitive or noncompetitive antagonist reshape the Emax/Hill dose-response curve in real time.

Medicine & Biophysics3DModerate60 FPS📱 Mobile-adapted
pharmacology ↗ Open standalone

This simulator renders a field of drug receptors on a cell membrane in 3D and drives their occupancy from the real Emax/Hill equation pharmacologists use to characterise receptor-targeted drugs. Titrate the agonist concentration on a log scale and watch receptors light up green as they bind, while a live dose-response curve traces the sigmoid response beneath. Switch on a competitive antagonist and the curve shifts rightward — more agonist is needed for the same effect, but the ceiling stays the same, because the antagonist can be out-competed. Switch to a noncompetitive antagonist instead and the ceiling itself drops, because those receptors are removed from the functional pool no matter how much agonist is added. Live readouts track fractional occupancy, response, and the apparent EC50/Emax exactly as a lab assay would report them.

⚙ Under the hood

Titrate an agonist against a 3D field of drug receptors and watch a competitive or noncompetitive antagonist reshape the Emax/Hill dose-response curve in real time.

pharmacologyreceptor bindingdose-responseHill equationmedicine3D

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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