🍄 Psilocybin Dose-Response Mystical Experience Simulator

Low-Dose Subtle Effects

Small placeholder note on subtle low-dose effects.

• 1–5 mg: Typical dose (placeholder range)
• Low: Subjective intensity (placeholder)
• Rare: Mystical content (placeholder)
• ~3–4 hr: Duration (placeholder)

Subtle mood and sensory shifts

Placeholder: mild mood lift and light sensory change at low dose.

Moderate-Dose Perceptual Changes

Short placeholder on rising perceptual change with dose.

• 10–15 mg: Typical dose (placeholder range)
• Moderate: Visual change (placeholder)
• Partial: Ego dissolution (placeholder)
• ~30 min: Onset (placeholder)

Perceptual and cognitive shifts scale with dose

Placeholder: visuals and thought patterns shift more as dose increases.

High-Dose Mystical Experience Threshold

Short placeholder describing the mystical-experience dose threshold.

• ~18–20 mg: Threshold dose (placeholder, sensitivity-adjusted)
• High: Mystical rate (placeholder)
• Common: Unity experience (placeholder)
• Strong: Ego dissolution (placeholder)

A dose threshold triggers full mystical-type states

Placeholder: crossing effective dose threshold reliably yields mystical content.

Mystical Experience Questionnaire Scoring

Short placeholder on MEQ30 scoring of the session.

• 0–100: MEQ scale (placeholder, composite score)
• ≥60: Complete experience (placeholder cutoff)
• 4: Domains (placeholder: unity, noetic, transcendence, ineffability)
• 30: Items (placeholder questionnaire length)

Four domains combine into one MEQ score

Placeholder: unity, sacredness, noetic quality, and ineffability sum to MEQ.

Correlation With Therapeutic Outcome

Short placeholder on MEQ predicting therapeutic outcome.

• Strong: Correlation (placeholder, MEQ vs outcome)
• +: Complete-experience bonus (placeholder threshold effect)
• Symptom change: Outcome measure (placeholder)
• Weeks–months: Follow-up (placeholder)

Higher MEQ predicts better clinical response

Placeholder: sessions crossing the complete-experience cutoff show larger gains.

Placeholder key insight: mystical intensity, not dose alone, best predicts benefit.