SLCO1B1 Statin Clearance — 2D Compartment & Strip-Chart Simulator

The gene SLCO1B1 encodes OATP1B1, the hepatic transporter that pulls statins out of the bloodstream and into the liver for clearance. Its common reduced-function variant is the single strongest known genetic risk factor for statin-induced muscle toxicity, especially with simvastatin. This 2D build models the same first-order elimination pharmacokinetics as a scrolling concentration strip chart with a live AUC-fill band, a radial myopathy-risk gauge, and a schematic gut→plasma→liver/muscle flow diagram whose gate capture probability is driven directly by the elimination rate constant. Pick a genotype, choose a statin, dose the patient, and watch plasma concentration, cumulative exposure and risk evolve in real time.