HomeMolecular BiologyPlanarian Regeneration: Wnt/β-catenin Field Map (2D)

Planarian Regeneration: Wnt/β-catenin Field Map (2D)

A 2D reaction-diffusion simulation of the Wnt/β-catenin morphogen field along a cut planarian's body axis, driving the same head/tail polarity switch as the 3D worm.

Molecular Biology2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-planarian-regeneration-stem-cell-signaling ↗ Open standalone

The same neoblast/blastema biology as the 3D worm, viewed as a 2D reaction-diffusion field. A morphogen concentration c(x,t) is integrated on a grid running along the amputated body's anterior–posterior axis with an explicit finite-difference solver — diffusion smooths it, decay clears it, a positional production term P(x) sets the baseline gradient, and a wound source switches on at the cut face as the blastema grows. The live field graph and colored tissue strip show that computation happening, rather than a static formula: suppressing signaling collapses both wounds toward head identity (double-headed), boosting it collapses both toward tail identity (double-tailed), exactly reproducing the textbook RNAi phenotypes from the field's own dynamics.

⚙ Under the hood

Cut a virtual planarian and watch a real reaction-diffusion field for Wnt/β-catenin signaling evolve along its body axis on a live 2D graph — dial the signaling level to reproduce the classic double-headed and double-tailed regeneration phenotypes from the field's own dynamics.

planarianstem-cellsregenerationwnt-signalingdevelopmental-biologyreaction-diffusionmolecular-biology

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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