HomeMolecular BiologyLiver Regeneration: Hepatocyte Regrowth Wave (2D)

Liver Regeneration: Hepatocyte Regrowth Wave (2D)

Interactive 2D cross-section simulation of liver regrowth after partial hepatectomy: a real reaction-diffusion (Fisher-KPP) wave of hepatocyte proliferation sweeps outward from the remnant tissue, with local growth throttled by hepatostat size-sensing feedback that you can disable to see unchecked overshoot.

Molecular Biology2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-organ-regeneration ↗ Open standalone

This 2D companion to the whole-organ 3D hepatostat simulation renders the same partial-hepatectomy regeneration as an actual spatial process: a cross-section of liver tissue in which local hepatocyte density both diffuses and proliferates, so the regrowth you watch is a genuine reaction-diffusion (Fisher–KPP) traveling wave sweeping out from the remnant tissue into the resected region — not an instant volumetric reveal keyed to a single mass number. The same hepatostat logistic brake and HGF/EGF decay pulse from the 3D model drive the local growth rate, so disabling the hepatostat toggle produces the same unchecked-overshoot failure mode, but now visibly as tissue density pushing past normal everywhere at once rather than a capped sphere. Adjust resection extent, growth-factor strength and simulation speed to see how each reshapes the advancing wavefront.

⚙ Under the hood

Interactive 2D cross-section simulation of liver regrowth after partial hepatectomy: a real reaction-diffusion (Fisher-KPP) wave of hepatocyte proliferation sweeps outward from the remnant tissue, with local growth throttled by hepatostat size-sensing feedback that you can disable to see unchecked overshoot.

liver regenerationhepatostatreaction-diffusionFisher-KPP wavehepatocyte proliferationcell biology

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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