HomeMolecular BiologyGap Junction Intercellular Coupling (2D)

Gap Junction Intercellular Coupling (2D)

2D top-down simulator of connexin gap junctions: a hexagonal tissue lattice of 61 cells diffuses a tracer signal cell-to-cell through gap-junction channels you can tune for density, Ca2+/pH gating and molecular-weight cutoff, with drag-pan, scroll-zoom and a live coupling strip-chart.

Molecular Biology2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-biology-ext-topic-74 ↗ Open standalone

This is the 2D top-down counterpart to the 3D gap-junction simulator. A hexagonal sheet of 61 cells is wired together by connexin gap junctions and the same diffusion-on-a-network model governs how a signalling molecule spreads from cell to cell through those channels — the 3D version was itself only a flat axial-coordinate graph viewed through a perspective camera, so this rendering solves and displays the identical mechanism directly from above. Pick the tracer species to see the connexin pore's molecular-weight cutoff in action, tune connexon channel density and Ca²⁺/pH-driven gating to couple or uncouple the tissue, click anywhere on the lattice to move the source, and drag-pan / scroll-zoom to inspect the ripple up close — with a live strip-chart tracking network mean concentration and coupling index alongside the instantaneous readouts.

⚙ Under the hood

2D top-down simulator of connexin gap junctions: a hexagonal tissue lattice of 61 cells diffuses a tracer signal cell-to-cell through gap-junction channels you can tune for density, Ca2+/pH gating and molecular-weight cutoff, with drag-pan, scroll-zoom and a live coupling strip-chart.

gap junctionconnexincell signallingdiffusionmolecular biologytissue coupling

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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