Home▸Molecular Biology▸Interrupted Mating: Population Recombinant-Frequency Curves

Interrupted Mating: Population Recombinant-Frequency Curves (2D)

Interactive 2D genetic-mapping simulator: a stochastic ensemble of thousands of independent Hfr x F- mating pairs, each with a randomly timed pilus contact and a randomly timed spontaneous bridge breakage, reproduces the real sigmoid recombinant-frequency-vs-time curves and declining marker plateaus from the classic Wollman-Jacob interrupted-mating experiment — a genuinely different, population-statistics counterpart to the single-pair 3D bead-chain model.

Molecular Biology2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version

Real interrupted-mating experiments never tracked a single bacterium — they mixed billions of Hfr donors with F^- recipients, sheared the whole culture apart at a chosen time, and measured what fraction of exconjugants had received each genetic marker. This 2D counterpart to the 3D single-pair bead-chain simulator rebuilds that actual measurement: thousands of independent simulated mating pairs, each with its own randomly timed pilus contact and randomly timed spontaneous bridge failure, are tracked live to produce the real sigmoid frequency-vs-time curves and the declining per-marker plateaus that made the original Wollman-Jacob technique a genetic-mapping tool in the first place.

⚙ Under the hood

Watch a stochastic population of thousands of independent Hfr x F- mating pairs — each with a randomly timed pilus contact and a randomly timed spontaneous bridge failure — build up the real sigmoid recombinant-frequency-vs-time curves and declining marker plateaus from the classic Wollman-Jacob interrupted-mating experiment.

conjugationplasmidHfrmolecular biologygene mappingmicrobiologypopulation statistics

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install