Home▸Medicine & Biophysics▸Stereocilia Tip-Link Gating Spring

Stereocilia Tip-Link Gating Spring

Interactive 3D model of cochlear hair-cell mechanotransduction: deflect a stereocilia bundle, watch tip-link tension gate MET ion channels, and see the adaptation motor reset the operating point in real time.

Medicine & Biophysics3DAdvanced60 FPS📱 Mobile-adapted⚡ Plasma⇄ 2D version
cochlear-hair-cell-mechanotransduction ↗ Open standalone

Cochlear hair cells convert mechanical motion into electricity through a single elegant mechanism: the tip link. This simulator renders a staircase bundle of stereocilia, deflects it under your control, and computes the tip-link tension, the Boltzmann open probability of the mechanotransduction channels it gates, and the resulting receptor current — all from the same gating-spring equations used in cochlear biophysics. A slow adaptation motor continuously resets the channels' operating point, reproducing the characteristic overshoot-and-relax response real hair cells show to a sustained deflection.

⚙ Under the hood

Adjust stereocilia bundle deflection and see how tip-link tension gates MET channels, affecting current flow.

hair cellmechanotransductionstereociliabiophysicscochleaion channel

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

What did you find?

Add reproduction steps (optional)