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Cytokine Storm Cascade: Multi-Organ Spread (2D)

2D network model of a cytokine storm spreading between six organs through a shared blood compartment: the same local positive-feedback loop as the 3D single-site scene, but coupled across the body by perfusion — a genuinely distinct 2D-native mechanism, not a flattened camera view.

Medicine & Biophysics2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version

This is the 2D network companion to the 3D single-site cytokine storm simulator. Instead of one well-mixed compartment, it runs the identical local positive-feedback loop — cytokine recruits immune cells, immune cells produce more cytokine — independently at six organs, then couples them through a shared, well-mixed blood pool via a perfusion exchange term. The result is a genuinely distinct, spatially-resolved view of the same physiology: whether a local infection stays contained or becomes a systemic, multi-organ storm now depends on a real parameter (vascular coupling) that the single-compartment 3D model has no room to express.

⚙ Under the hood

cytokine stormsepsisimmune systemmulti-organ dysfunctionpositive feedbackcritical care

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

How does this differ from the 3D cytokine storm sim?

The 3D scene models one well-mixed site. This 2D version runs the same local feedback loop at six organs and links them through a shared blood compartment, so it can show whether and how fast the storm spreads to distant organs — something a single-compartment model cannot represent.

What does the vascular coupling slider control?

It sets the perfusion exchange rate between each organ and the shared blood pool. Low coupling can let the origin organ's storm stay local or burn out; high coupling lets circulating cytokine seed the same feedback loop at other organs before the origin resolves.