DBS Desynchronization 2D: Basal Ganglia Phase-Circle
Interactive 2D Kuramoto model of subthalamic-nucleus neurons locking into pathological beta-band synchrony in Parkinson's disease: an anatomical cross-section view plus a live phase-circle order-parameter plot showing how deep brain stimulation pulses desynchronize (or fail to) depending on frequency, amplitude and coupling strength.
In Parkinson's disease, neurons in the subthalamic nucleus fall into excessive beta-band (13–30 Hz) synchrony, and that pathological synchrony is thought to underlie bradykinesia and rigidity. This 2D companion renders 180 STN neurons as coupled phase oscillators (a Kuramoto model) on two linked panels — a real anatomical cross-section showing the DBS electrode's volume of tissue activated, and a phase-circle plot of the population's order parameter r·e^(iψ) — tracked live as the recurrent coupling strength K, and a real deep brain stimulation pulse train's frequency, amplitude and reach, are tuned in real time. Both panels are computed directly in the plane from the same governing equations as the 3D version, letting you see the spatial reach of the electrode and the degree of phase-locking side by side.
A 2D Kuramoto-model network of 180 subthalamic-nucleus neurons, shown on a real anatomical cross-section alongside a live phase-circle order-parameter plot. Tune a deep brain stimulation electrode's pulse frequency, amplitude and coupling strength and watch both the spatial volume of tissue activated and the population's phase-locking respond in real time.
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install