HomeMedicine & BiophysicsBaroreflex Closed-Loop Pressure Recovery (2D)

Baroreflex Closed-Loop Pressure Recovery (2D)

Interactive 2D closed-loop model of the arterial baroreflex: instead of just placing pressure on a static sigmoid, this dynamically integrates the feedback loop over time — trigger a haemorrhage bolus or orthostatic challenge and watch mean arterial pressure actually recover along the firing-rate sigmoid, with a live time-domain strip chart of pressure and heart rate and a predicted-vs-actual steady-state readout for sustained disturbances.

Medicine & Biophysics2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version
2d-baroreflex-blood-pressure-regulation ↗ Open standalone

The arterial baroreflex does not just read pressure off a fixed sigmoid curve — it actively closes the loop, using afferent nerve firing to drive autonomic outflow that pulls pressure back toward a set-point over real time. This 2D simulator integrates that closed-loop control law directly: trigger a haemorrhage bolus or an orthostatic "stand up" challenge and watch mean arterial pressure trace an actual recovery trajectory along the same firing-rate sigmoid used by the 3D model, while a scrolling strip chart plots pressure and heart rate as continuous time-series. A sustained external pressor/depressor drive demonstrates the classic proportional-control signature of the real reflex: it dampens a persistent disturbance but cannot fully cancel it, settling at a predictable steady-state offset from the set-point that you can compare directly against the model's own closed-form prediction.

⚙ Under the hood

Interactive 2D closed-loop model of the arterial baroreflex: instead of placing pressure on a static sigmoid, this integrates the feedback loop forward in time — trigger a haemorrhage bolus or an orthostatic 'stand up' challenge and watch mean arterial pressure actually recover along the firing-rate sigmoid, with a scrolling time-domain strip chart of pressure and heart rate and a predicted-vs-actual steady-state readout for sustained disturbances.

baroreflexblood pressurecardiovascular physiologyclosed-loop controlautonomic nervous systemsigmoid curvehomeostasis

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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