🦋 Lupus Nephritis Staging Simulator

Minimal and Mesangial Lupus Nephritis

Placeholder: earliest classes show mild mesangial deposition only.

• Mesangium: Deposit site (Placeholder text)
• None/mild: Proliferation (Placeholder text)
• Observation: Typical therapy (Placeholder text)
• Excellent: Prognosis (Placeholder text)

Histology overview

Placeholder sentence describing class I-II findings briefly.

Placeholder key insight sentence.

Focal and Diffuse Proliferative Nephritis

Placeholder: proliferative classes drive most severe renal injury.

• <50% / ≥50%: Loops involved (Placeholder text)
• Common: Crescents (Placeholder text)
• Cyclophosphamide: Typical therapy (Placeholder text)
• Guarded: Prognosis (Placeholder text)

Histology overview

Placeholder sentence describing class III-IV findings briefly.

Placeholder key insight sentence.

Membranous Lupus Nephropathy

Placeholder: subepithelial deposits create characteristic GBM spikes.

• Subepithelial: Deposit site (Placeholder text)
• Nephrotic range: Presentation (Placeholder text)
• Mycophenolate: Typical therapy (Placeholder text)
• Variable: Prognosis (Placeholder text)

Histology overview

Placeholder sentence describing class V findings briefly.

Placeholder key insight sentence.

Advanced Sclerosing Lupus Nephritis

Placeholder: irreversible global sclerosis of glomeruli.

• ≥90% globally: Sclerosis (Placeholder text)
• Often ESRD: Function (Placeholder text)
• Supportive/RRT: Typical therapy (Placeholder text)
• Poor: Prognosis (Placeholder text)

Histology overview

Placeholder sentence describing class VI findings briefly.

Placeholder key insight sentence.

Immunosuppressive Therapy by Class

Placeholder: drug choice follows biopsy class and activity index.

• Class III–V: Mycophenolate (Placeholder text)
• Class III–IV severe: Cyclophosphamide (Placeholder text)
• Adjunct all classes: Steroids (Placeholder text)
• Transplant workup: Class VI (Placeholder text)

Therapy overview

Placeholder sentence describing therapy selection briefly.

Placeholder key insight sentence.