💉 GLP-1 Muscle Mass Preservation Strategy Simulator

Baseline Body Composition

Placeholder lead: fat and lean mass before any GLP-1 intervention starts.

• ~30%: Typical fat mass (placeholder baseline share)
• ~70%: Typical lean mass (placeholder baseline share)
• Appetite ↓: GLP-1 mechanism (placeholder short note)
• 6–12 mo: Weight loss horizon (placeholder timeline)

Why baseline composition matters

Placeholder section text: fat vs lean split sets the reference point for tracking losses.

GLP-1 Therapy and the Caloric Deficit

Placeholder lead: appetite suppression creates a deficit pulling from both tissue types.

• Appetite ↓: Deficit source (placeholder mechanism note)
• ~6%: Early total loss (placeholder body weight)
• Fat + lean: Loss source (placeholder composition)
• Early months: Risk window (placeholder timing)

Deficit draws from both compartments

Placeholder section text: rapid loss pulls energy from fat stores and lean tissue alike.

Unaddressed Muscle Loss Risk

Placeholder lead: lean mass can reach roughly 40 percent of total weight lost.

• ~40%: Lean share (unmanaged) (placeholder of total loss)
• ~60%: Fat share (unmanaged) (placeholder of total loss)
• Strength ↓: Functional risk (placeholder consequence)
• RMR ↓: Metabolic risk (placeholder consequence)

Why unmanaged loss skews lean

Placeholder section text: deficit alone does not protect muscle tissue from being metabolized.

Resistance Training + Protein Intervention

Placeholder lead: training and protein intake redirect loss toward fat stores.

• 0–5 /wk: Training lever (placeholder session range)
• 0.8–2.0 g/kg: Protein lever (placeholder intake range)
• ~8%: Best-case lean share (placeholder of total loss)
• Anabolic signal: Mechanism (placeholder short note)

Two levers that preserve lean tissue

Placeholder section text: mechanical loading plus amino acid supply protect muscle protein.

Outcome Comparison — Same Weight, Different Composition

Placeholder lead: identical total loss can mean very different fat-to-lean outcomes.

• 13%: Total loss (both paths) (placeholder body weight)
• ~40%: Unmanaged lean loss (placeholder of loss)
• ~8–15%: Managed lean loss (placeholder of loss)
• 0–100: Preservation score range (placeholder scale)

Composition, not just the scale, matters

Placeholder section text: two paths to the same weight loss diverge sharply in body composition.

Placeholder highlight: prioritizing lean mass preservation changes long-term outcomes.