Baseline Body Composition
Placeholder lead: fat and lean mass before any GLP-1 intervention starts.
- ~30%: Typical fat mass (placeholder baseline share)
- ~70%: Typical lean mass (placeholder baseline share)
- Appetite ↓: GLP-1 mechanism (placeholder short note)
- 6–12 mo: Weight loss horizon (placeholder timeline)
Why baseline composition matters
Placeholder section text: fat vs lean split sets the reference point for tracking losses.
GLP-1 Therapy and the Caloric Deficit
Placeholder lead: appetite suppression creates a deficit pulling from both tissue types.
- Appetite ↓: Deficit source (placeholder mechanism note)
- ~6%: Early total loss (placeholder body weight)
- Fat + lean: Loss source (placeholder composition)
- Early months: Risk window (placeholder timing)
Deficit draws from both compartments
Placeholder section text: rapid loss pulls energy from fat stores and lean tissue alike.
Unaddressed Muscle Loss Risk
Placeholder lead: lean mass can reach roughly 40 percent of total weight lost.
- ~40%: Lean share (unmanaged) (placeholder of total loss)
- ~60%: Fat share (unmanaged) (placeholder of total loss)
- Strength ↓: Functional risk (placeholder consequence)
- RMR ↓: Metabolic risk (placeholder consequence)
Why unmanaged loss skews lean
Placeholder section text: deficit alone does not protect muscle tissue from being metabolized.
Resistance Training + Protein Intervention
Placeholder lead: training and protein intake redirect loss toward fat stores.
- 0–5 /wk: Training lever (placeholder session range)
- 0.8–2.0 g/kg: Protein lever (placeholder intake range)
- ~8%: Best-case lean share (placeholder of total loss)
- Anabolic signal: Mechanism (placeholder short note)
Two levers that preserve lean tissue
Placeholder section text: mechanical loading plus amino acid supply protect muscle protein.
Outcome Comparison — Same Weight, Different Composition
Placeholder lead: identical total loss can mean very different fat-to-lean outcomes.
- 13%: Total loss (both paths) (placeholder body weight)
- ~40%: Unmanaged lean loss (placeholder of loss)
- ~8–15%: Managed lean loss (placeholder of loss)
- 0–100: Preservation score range (placeholder scale)
Composition, not just the scale, matters
Placeholder section text: two paths to the same weight loss diverge sharply in body composition.
Placeholder highlight: prioritizing lean mass preservation changes long-term outcomes.