HomeEnvironmental Toxicology & ExposomeToxic Body Burden: Multi-Route Toxicokinetics Simulator

Toxic Body Burden: Multi-Route Toxicokinetics Simulator

Interactive two-compartment toxicokinetics simulator: dose a xenobiotic via inhalation, ingestion or dermal contact, watch it partition between blood and fatty tissue, and track body burden, half-life and elimination in real time.

Environmental Toxicology & Exposome3DModerate60 FPS
toxic-substances-pollution ↗ Open standalone

How does a pollutant actually accumulate inside a living body? This simulator models a xenobiotic entering through inhalation, ingestion or dermal contact, distributing between a blood compartment and a fatty-tissue compartment, and leaving through metabolic clearance — the same two-compartment first-order kinetics environmental toxicologists use to describe how persistent lipophilic pollutants like PCBs, dioxins and PFAS build up in tissue over chronic, repeated exposure. Instanced particles stream from the chosen exposure route into the bloodstream and settle into the fat depot at a rate set by the toxicant's lipophilicity, while live readouts track blood concentration, accumulated body burden and the compartment's elimination half-life as the exposure runs.

⚙ Under the hood

Dose a xenobiotic via inhalation, ingestion or dermal contact and watch a two-compartment toxicokinetic model distribute it between blood and fatty tissue, tracking body burden and elimination half-life as lipophilicity and exposure change.

toxicologytoxicokineticsbioaccumulationenvironmental-healthpharmacokineticsexposome

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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