🌾 Erythema Migrans & Lyme Disease Staging Simulator

Tick Attachment and Borrelia Inoculation

Placeholder: infection begins with a tick bite delivering spirochetes.

• Ixodes: Vector (Placeholder short note)
• 36–48h: Attach time (Placeholder short note)
• B. burgdorferi: Pathogen (Placeholder short note)
• Local skin: Bite site (Placeholder short note)

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Placeholder short paragraph about tick bite entry.

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Early Localized Erythema Migrans

Placeholder: the classic expanding bullseye rash develops.

• 3–14 days: Onset (Placeholder short note)
• 2–3 cm/day: Rash growth (Placeholder short note)
• Bullseye: Shape (Placeholder short note)
• ~70–80%: Frequency (Placeholder short note)

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Placeholder short paragraph about EM rash formation.

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Hematogenous Dissemination of Spirochetes

Placeholder: spirochetes spread via blood to distant tissues.

• Days–weeks: Window (Placeholder short note)
• Bloodstream: Route (Placeholder short note)
• Skin, joints, CNS: Targets (Placeholder short note)
• PCR/culture: Detectability (Placeholder short note)

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Placeholder short paragraph about dissemination.

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Early Disseminated Lyme — Multiple EM and Neuro Signs

Placeholder: secondary rashes and early neurologic symptoms emerge.

• 3–10 weeks: Timing (Placeholder short note)
• Multiple sites: Secondary EM (Placeholder short note)
• Facial palsy: Neuro signs (Placeholder short note)
• AV block: Cardiac risk (Placeholder short note)

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Placeholder short paragraph about early disseminated stage.

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Late-Stage Lyme — Joint and CNS Involvement

Placeholder: untreated disease progresses to arthritis and neuroborreliosis.

• Months: Onset (Placeholder short note)
• Large joints: Arthritis (Placeholder short note)
• Encephalopathy: CNS (Placeholder short note)
• Partial: Reversibility (Placeholder short note)

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Placeholder short paragraph about late-stage involvement.

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