🌾 Gluten-Free Diet Adherence Simulator

Diet Initiation Baseline

Placeholder: starting point before gluten elimination begins.

• >10x ULN: tTG-IgA baseline (Placeholder metric)
• High: Symptom score (Placeholder metric)
• Marsh 3: Villous atrophy (Placeholder metric)
• 0 mo: Diet duration (Placeholder metric)

Baseline serology and symptoms

Placeholder short paragraph describing pre-diet antibody and symptom state.

Strict Adherence — 3-Month Mark

Placeholder: early response window under strict adherence.

• -30%: tTG-IgA change (Placeholder metric)
• Partial: Symptom relief (Placeholder metric)
• >95%: Adherence needed (Placeholder metric)
• 3 mo: Follow-up (Placeholder metric)

Early adherence response

Placeholder short paragraph on the three-month adherence checkpoint.

tTG Antibody Decline

Placeholder: sustained decline in tTG titers over months.

• ~4-6 mo: Half-life estimate (Placeholder metric)
• <20 U/mL: Normal range (Placeholder metric)
• High impact: Strictness effect (Placeholder metric)
• 6-12 mo: Typical timeline (Placeholder metric)

Titer decay dynamics

Placeholder short paragraph describing the antibody decay curve.

Symptom Resolution

Placeholder: symptoms fade as mucosal healing progresses.

• Weeks: GI symptom relief (Placeholder metric)
• 1-2 yrs: Mucosal healing (Placeholder metric)
• Months: Fatigue resolution (Placeholder metric)
• Improved: Quality of life (Placeholder metric)

Symptom-antibody relationship

Placeholder short paragraph on symptom lag behind serology.

Accidental Exposure Setback Risk

Placeholder: cross-contamination causes temporary antibody spikes.

• +20-40%: Exposure spike (Placeholder metric)
• Weeks: Recovery time (Placeholder metric)
• Cross-contact: Common sources (Placeholder metric)
• Elevated: Risk with low strictness (Placeholder metric)

Managing accidental exposure

Placeholder short paragraph on setback risk and recovery.

Placeholder: strict adherence lowers both spike size and recovery time.