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Polygenic Embryo Selection (2D): Selection Differential Simulator

Interactive 2D quantitative-genetics simulator: score a batch of embryos on a polygenic index against the population bell curve, select the top-k, and watch the breeder's equation R = h²S predict how much the selected group's expected trait actually shifts. Pan and zoom the distribution plot.

Preimplantation Genetic Testing2DModerate60 FPS📱 Mobile-adapted⇄ 3D version

Details

CategoryPreimplantation Genetic Testing

RenderingCanvas 2D

DifficultyModerate

Target FPS60

ControlsSliders set embryo batch size, how many top-scoring embryos are selected, and the trait's heritability; a dropdown switches between maximizing a trait index or minimizing a disease-risk index; a button draws a fresh randomized batch; drag the plot to pan and scroll/pinch to zoom the distribution view.

geneticsbioethicspolygenic scorequantitative geneticsembryo selectionstatistics2D

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This simulator visualizes the actual statistics behind polygenic embryo screening. A batch of embryos is drawn as standardized polygenic-index z-scores against the population's bell curve; choosing the top-k by index carves out a selection differential S, and the breeder's equation R = h²S converts that differential into the realistic expected trait shift once heritability is accounted for. Adjust batch size, how many embryos are "selected", and the trait's heritability to see why real polygenic scores move outcomes only slightly — the core quantitative fact behind the bioethics debate over ELSI, informed consent, and designer-baby claims covered in the accompanying article on the ethics of genetic research. Drag the plot to pan and scroll or pinch to zoom into the distribution.

⚙ Under the hood

2D bell-curve view of polygenic embryo screening: score a batch of embryos as z-scores against the population distribution, select the top-k, and watch the breeder's equation R = h²S convert that selection differential into a realistic expected trait shift. Drag to pan and scroll to zoom the plot.

geneticsbioethicspolygenic scorequantitative geneticsembryo selectionstatistics2D

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install