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Polygenic Embryo Selection: Selection Differential Simulator

Interactive quantitative-genetics simulator: score a batch of embryos on a polygenic index, select the top-k, and watch the breeder's equation R = h²S predict how much the selected group's expected trait actually shifts.

Preimplantation Genetic Testing3DModerate60 FPS

This simulator visualizes the actual statistics behind polygenic embryo screening. A batch of embryos is drawn as standardized polygenic-index z-scores against the population's bell curve; choosing the top-k by index carves out a selection differential S, and the breeder's equation R = h²S converts that differential into the realistic expected trait shift once heritability is accounted for. Adjust batch size, how many embryos are "selected", and the trait's heritability to see why real polygenic scores move outcomes only slightly — the core quantitative fact behind the bioethics debate over ELSI, informed consent, and designer-baby claims covered in the accompanying article on the ethics of genetic research.

⚙ Under the hood

Score a batch of embryos on a standardized polygenic index against the population bell curve, select the top-k, and watch the breeder's equation R = h²S convert that selection differential into a realistic expected trait shift.

geneticsbioethicspolygenic scorequantitative geneticsembryo selectionstatistics

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install