HomeNeuroscience & Biophysics3D Dendritic Spine Plasticity

3D Dendritic Spine Plasticity

Orbit a real 3D dendrite segment as instanced spine meshes grow, shrink, sprout and retract along its surface, each driven by its own leaky-integrator calcium trace of local activity — structural plasticity rendered in 3D.

Neuroscience & Biophysics3DModerate60 FPS📱 Mobile-adapted⇄ 2D version
3d-neurobiology-plasticity ↗ Open standalone

This is the three-dimensional counterpart to the Dendritic Spine Plasticity Lab: a real dendrite segment, modeled as a curved 3D tube you can orbit and zoom, studded with instanced spine meshes that grow, shrink, sprout and retract in real time. Every spine runs its own leaky-integrator calcium trace of local synaptic activity, and its live structural size and calcium level are rendered directly as head radius and color — no discrete spike network, no synaptic-weight learning, just the structural half of plasticity playing out across an actual 3D surface. Drag a local burst zone to a position along the dendrite, add a spontaneous background rate, or trigger a deprivation pulse, and watch which patches of the dendrite densify and which thin out.

⚙ Under the hood

Explore activity-dependent structural changes in a realistic 3D dendrite segment, with spines modeled as stalk-and-head meshes. Visualize spine growth/shrink/prune dynamics and calcium levels through interactive controls.

neurosciencestructural plasticitydendritic spinescalcium signalingsynaptogenesis

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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