Frustrated Phagocytosis: Fiber Pathogenicity Paradigm (2D)

This is the 2D counterpart to the 3D macrophage-vs-nanofiber scene, computing the identical length–diameter–rigidity–biopersistence biophysics through a live side-on cross-section and two supporting charts instead of a rendered 3D cell. Watch the phagocytic cup either zipper shut around the fiber, stall into frustrated phagocytosis with a continuous burst of ROS and cytokines from the open interface, or watch the fiber dissolve away before it finishes the job — while a length-vs-reach diagram and a cup-closure/ROS strip chart track exactly why.