HomeMolecular BiologyGene Regulatory Network Oscillator

Gene Regulatory Network Oscillator

Interactive 3D Goodwin-model gene oscillator: a single gene, its mRNA, protein and a delayed repressor form a negative-feedback loop. Tune Hill cooperativity and decay rates to cross the bifurcation between damped and sustained oscillation, and watch the limit cycle trace out in phase space.

Molecular Biology3DAdvanced60 FPS📱 Mobile-adapted⇄ 2D version
gene-regulatory-network-oscillator ↗ Open standalone

A single gene can oscillate all by itself if its own output eventually shuts its own transcription down — with enough delay and enough cooperativity in the repression. This simulator renders the classic Goodwin model: mRNA X, protein Y and a repressor Z chained in a negative-feedback loop, each represented as a pulsing node whose glow tracks its live concentration, plus a phase-space trail that traces the trajectory of (X, Y, Z) through 3D concentration space. Tune the Hill cooperativity exponent past Griffith's stability threshold and watch the system cross the bifurcation from a damped spiral into steady state to a genuine self-sustaining limit cycle — the same mathematical structure that drives real circadian and synthetic genetic clocks.

⚙ Under the hood

Interactive 3D Goodwin-model gene oscillator: a single gene's mRNA, protein and a delayed repressor form a negative-feedback loop. Tune Hill cooperativity and decay rates to cross the bifurcation between damped decay and a sustained limit cycle, and watch the trajectory trace out in phase space.

gene regulationGoodwin oscillatornegative feedbacksystems biologyHill functionlimit cycle

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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