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mRNA Capping Kinetics: Cap0/Cap1 Formation vs Degradation Race

Interactive 3D reactor of mRNA molecules racing through the co-transcriptional capping pathway: tune the capping enzyme, the 2'-O-methyltransferase and exonuclease degradation rates and watch the Cap0/Cap1/degraded fractions evolve live.

Molecular Biology3DAdvanced60 FPS📱 Mobile-adapted⇄ 2D version

Every mRNA molecule leaving in-vitro transcription runs a race: the capping enzyme and 2'-O-methyltransferase must convert it to translation-competent, immune-silent Cap1 before an exonuclease chews it up. This simulator drops a batch of individually-tracked mRNA particles into a 3D reactor, gives each one its own continuous-time Markov trajectory through Uncapped → Cap0 → Cap1 (or → Degraded), and lets you tune the capping rate, the methyltransferase rate, the degradation rate and the reactor temperature to see how a real GMP process turns rate constants into batch-release-quality Cap1 yield.

⚙ Under the hood

A 3D reactor of individually-tracked mRNA molecules races through the co-transcriptional capping pathway (Cap0 then Cap1) while a competing exonuclease degrades whatever is still uncapped, letting you tune enzyme rates and temperature to see how GMP process parameters set batch Cap1 yield.

mRNAbiotechnologyenzyme kineticsGMPmolecular biologyquality control

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install