Home▸Molecular Biology▸Liposome Bilayer Domains — Phase-Field Release (2D)

Liposome Bilayer Domains — Phase-Field Release (2D)

2D lattice companion simulator: a Glauber-dynamics gel/fluid domain field on the lipid bilayer patch drives an emergent, cooperativity-sharpened permeability that releases drug through localized grain-boundary gates around a liposome cross-section — the same first-order release kinetics as the 3D shell version, computed by a genuinely distinct 2D mechanism.

Molecular Biology2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version

Details

CategoryMolecular Biology

RenderingCanvas 2D

DifficultyAdvanced

Target FPS60

ControlsPick a lipid preset (DMPC/DPPC/DSPC) to set the phase-transition temperature, drag sliders for bath temperature, transition cooperativity (width), and simulation speed, and use Reset to reseed the lattice domain field and the liposome cross-section with fresh encapsulated drug.

liposomedrug deliveryphase transitionmembrane permeabilitypharmacokineticsnanomedicinelattice modelIsing dynamics

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This 2D companion to the thermosensitive-liposome shell simulator drives the identical first-order release kinetics from a genuinely distinct mechanism: a 48×48 Glauber-dynamics lattice field simulates the bilayer's gel/fluid domains directly, producing an emergent, cooperativity-sharpened permeability instead of a plugged-in sigmoid formula, then maps the lattice's own grain-boundary "packing defects" onto angular exit gates around a liposome cross-section so drug escapes through the same simulated domain boundaries the theory describes.

⚙ Under the hood

A 48×48 Glauber-dynamics lattice simulates the lipid bilayer's own gel/fluid domains, producing an emergent, cooperativity-sharpened permeability that gates drug release through localized grain-boundary defects around a liposome cross-section — the same first-order release kinetics as the 3D shell version, computed by a genuinely distinct 2D phase-field mechanism.

liposomedrug deliveryphase transitionmembrane permeabilitypharmacokineticsnanomedicinelattice modelIsing dynamics

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install