HomeMolecular BiologyCytokinesis: Contractile Ring Constriction (2D)

Cytokinesis: Contractile Ring Constriction (2D)

Interactive 2D simulator of the cytokinetic contractile ring: 72 discrete actomyosin nodes under purse-string tension constrict a dividing cell's equator, with myosin-II activity, cortical resistance and RhoA zone width tunable in real time alongside live ring radius, ingression rate and irregularity readouts.

Molecular Biology2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-biology-ext-topic-42 ↗ Open standalone

This 2D companion to the 3D Contractile Ring simulator views the dividing cell's equator face-on: 72 discrete actomyosin nodes, each carrying its own local ring radius, contract under a Laplace-type purse-string tension while a cortical coupling term lets neighbouring nodes exchange a little of that tension and smooth out local irregularities — a real particle-based mechanism rather than a redraw of the 3D scene, whose continuum limit reduces exactly to the same T/R tension law. Dial in myosin-II motor activity, cortical resistance and the width of the RhoA-active equatorial zone to see how each reshapes the furrow, or add a Latrunculin-like actin poison to watch a stalled furrow's nodes relax back open, while live readouts track ring radius, ingression rate, elapsed division time and the ring's own irregularity.

⚙ Under the hood

Interactive 2D simulator of the cytokinetic contractile ring: 72 discrete actomyosin nodes under purse-string tension constrict a dividing cell's equator, with myosin-II activity, cortical resistance and RhoA zone width tunable in real time alongside live ring radius, ingression rate and irregularity readouts.

cell biologymitosiscytokinesisactomyosincell divisionbiophysics

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

What did you find?

Add reproduction steps (optional)