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Microencapsulated Probiotic GI Delivery — 2D Cross-Section

Interactive 2D cross-section simulator: engineered probiotic capsules travel down a schematic gut path, their enteric shell dissolving by local pH while bacterial viability decays under acid exposure — tune shell thickness, coating trigger pH, transit time and strain acid-tolerance, then drag to pan and scroll to zoom the path.

Microbiome & Metabolic Engineering2DModerate60 FPS📱 Mobile-adapted⇄ 3D version

Details

CategoryMicrobiome & Metabolic Engineering

RenderingCanvas 2D

DifficultyModerate

Target FPS60

ControlsFour sliders (enteric shell thickness, coating trigger pH, total GI transit time, strain acid sensitivity) drive the live capsule cohort; a Re-dose button reseeds all capsules at the mouth. Drag the canvas to pan and scroll the mouse wheel (or use the +/− buttons) to zoom into any region of the gut path; a Reset view button restores the default framing.

microbiomeprobioticsdrug-deliverygutph-simulationencapsulationbiotech

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Delivering an engineered microbiome therapeutic to the gut is not just a biology problem — it's an encapsulation-engineering problem. This 2D simulator sends a cohort of pH-responsive microcapsules along a flattened, schematic gastrointestinal path, dissolving each capsule's enteric shell only once the surrounding pH crosses a tunable trigger, while the bacteria inside decay in viability at very different rates depending on whether the shell still shields them. Adjust shell thickness, coating trigger pH, total transit time and the strain's own acid tolerance to see how each design choice trades protection against a wasted, never-released dose — with live readouts of shell integrity, mean viability, and the fraction of the cohort actually delivering a viable dose to the colon. Drag the canvas to pan and scroll (or use the +/− buttons) to zoom into any region of the path.

⚙ Under the hood

A 2D cross-section simulator sends a cohort of pH-responsive probiotic microcapsules along a schematic gut path, dissolving each enteric shell only once local pH crosses a tunable trigger while bacterial viability decays under acid exposure. Tune shell thickness, trigger pH, transit time and strain acid-tolerance, and drag to pan or scroll to zoom the path.

microbiomeprobioticsdrug-deliverygutph-simulationencapsulationbiotech

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install