HomeMetabolomics & Biofluid ProfilingQC Drift Correction in Metabolomics Runs

QC Drift Correction in Metabolomics Runs

Interactive 3D metabolomics QC-drift simulator: watch instrument sensitivity decay and batch shifts corrupt an LC-MS run, then apply pooled-QC-based drift correction and see %RSD collapse in real time.

Metabolomics & Biofluid Profiling3DModerate60 FPS
biology-ext-topic-18 ↗ Open standalone

Every LC-MS or GC-MS metabolomics batch drifts: electrospray sources foul, columns age, and detector sensitivity slowly decays over hundreds of injections — sometimes with a sudden step when a run is split across batches. This simulator renders a full injection sequence in 3D across four metabolite panels, with pooled QC samples (identical composition, injected on a fixed interval) tracing out the instrument's true drift curve. Toggle drift severity, QC frequency and a batch step-shift to corrupt the run, then apply QC-based drift correction and watch the QC %RSD collapse in real time — the same quality-control workflow every untargeted metabolomics lab runs before trusting a single peak.

⚙ Under the hood

Interactive 3D LC-MS run simulator: pooled QC injections trace instrument sensitivity drift and batch step-shifts across four metabolite panels, and a live drift-correction toggle shows QC %RSD collapse in real time.

metabolomicsmass spectrometryquality controlbatch effectsLC-MSanalytical chemistry

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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