HomeMetabolomics & Biofluid ProfilingQC Drift Correction in Metabolomics Runs (2D)

QC Drift Correction in Metabolomics Runs (2D)

Interactive 2D metabolomics QC-drift simulator: watch instrument sensitivity decay and batch shifts corrupt an LC-MS run across four scrollable metabolite strip-charts, then apply pooled-QC drift correction and see %RSD collapse in real time.

Metabolomics & Biofluid Profiling2DModerate60 FPS📱 Mobile-adapted⇄ 3D version
2d-biology-ext-topic-18 ↗ Open standalone

Every LC-MS or GC-MS metabolomics batch drifts: electrospray sources foul, columns age, and detector sensitivity slowly decays over hundreds of injections — sometimes with a sudden step when a run is split across batches. This simulator renders a full injection sequence across four stacked, pannable and zoomable strip-charts, one per metabolite, with pooled QC samples (identical composition, injected on a fixed interval) tracing out the instrument's true drift curve. Toggle drift severity, QC frequency and a batch step-shift to corrupt the run, then apply QC-based drift correction and watch the QC %RSD collapse in real time — the same quality-control workflow every untargeted metabolomics lab runs before trusting a single peak.

⚙ Under the hood

Interactive 2D LC-MS run simulator: pooled QC injections trace instrument sensitivity drift and batch step-shifts across four scrollable, zoomable metabolite strip-charts, and a live drift-correction toggle shows QC %RSD collapse in real time.

metabolomicsmass spectrometryquality controlbatch effectsLC-MSanalytical chemistry

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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