🧠 Cerebral Autoregulation: How the Brain Keeps Its Own Blood Flow Constant
Explore how the brain maintains steady cerebral blood flow across a wide range of blood pressures through myogenic, metabolic and neurogenic autoregulation, and why this system fails in stroke and traumatic brain injury.
This simulation shows how cerebral blood flow stays nearly constant across a broad range of arterial pressures, and how the pressure-flow curve changes shape when autoregulatory mechanisms are impaired or when carbon dioxide levels shift.
🔬 What It Demonstrates
This simulation shows how cerebral blood flow stays nearly constant across a broad range of arterial pressures, and how the pressure-flow curve changes shape when autoregulatory mechanisms are impaired or when carbon dioxide levels shift.
🎮 How to Use
Adjust mean arterial pressure and CO2 levels with the sliders and watch how cerebral blood flow responds, then toggle impaired autoregulation to see how the protective plateau collapses.
💡 Did You Know?
A single breath-holding episode can raise CO2 enough to noticeably increase cerebral blood flow, while brief hyperventilation can lower it just as quickly, which is why controlled breathing is sometimes used to manage intracranial pressure in emergencies.
Explore how the brain maintains steady cerebral blood flow across a wide range of blood pressures through myogenic, metabolic and neurogenic autoregulation, and why this system fails in stroke and traumatic brain injury.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install