⚖️ Calcium Homeostasis: How Parathyroid Hormone Balances Blood Calcium
Explore how parathyroid hormone and calcitonin work together to keep blood calcium within a razor-thin range, and why even small deviations can trigger tetany or bone disease.
The simulation visualizes the real-time feedback loop between blood calcium, parathyroid hormone, bone resorption, renal reabsorption, and vitamin D activation, showing how the body corrects hypocalcemia and hypercalcemia within a 3D model of the glands and target organs.
🔬 What It Demonstrates
The simulation visualizes the real-time feedback loop between blood calcium, parathyroid hormone, bone resorption, renal reabsorption, and vitamin D activation, showing how the body corrects hypocalcemia and hypercalcemia within a 3D model of the glands and target organs.
🎮 How to Use
Adjust the dietary calcium intake and simulated parathyroid activity sliders to see how PTH secretion, osteoclast activity, and calcitriol levels respond, and watch the blood calcium gauge move back toward the normal 8.5 to 10.5 mg/dL range.
💡 Did You Know?
The four parathyroid glands together weigh only about 120 milligrams total, roughly the size of a few grains of rice, yet the hormone they produce is powerful enough to reshape the entire skeleton over a lifetime if left chronically overactive.
Explore how parathyroid hormone and calcitonin work together to keep blood calcium within a razor-thin range, and why even small deviations can trigger tetany or bone disease.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install