The simulation visualizes the real-time feedback loop between blood calcium, parathyroid hormone, bone resorption, renal reabsorption, and vitamin D activation, showing how the body corrects hypocalcemia and hypercalcemia within a 3D model of the glands and target organs.
Adjust the dietary calcium intake and simulated parathyroid activity sliders to see how PTH secretion, osteoclast activity, and calcitriol levels respond, and watch the blood calcium gauge move back toward the normal 8.5 to 10.5 mg/dL range.
Sliders control dietary calcium intake and parathyroid gland activity, while the display updates blood calcium, PTH, bone resorption, and vitamin D activation levels in real time.
The four parathyroid glands together weigh only about 120 milligrams total, roughly the size of a few grains of rice, yet the hormone they produce is powerful enough to reshape the entire skeleton over a lifetime if left chronically overactive.
The simulation visualizes the real-time feedback loop between blood calcium, parathyroid hormone, bone resorption, renal reabsorption, and vitamin D activation, showing how the body corrects hypocalcemia and hypercalcemia within a 3D model of the glands and target organs.
The simulation visualizes the real-time feedback loop between blood calcium, parathyroid hormone, bone resorption, renal reabsorption, and vitamin D activation, showing how the body corrects hypocalcemia and hypercalcemia within a 3D model of the glands and target organs.
Adjust the dietary calcium intake and simulated parathyroid activity sliders to see how PTH secretion, osteoclast activity, and calcitriol levels respond, and watch the blood calcium gauge move back toward the normal 8.5 to 10.5 mg/dL range.
The four parathyroid glands together weigh only about 120 milligrams total, roughly the size of a few grains of rice, yet the hormone they produce is powerful enough to reshape the entire skeleton over a lifetime if left chronically overactive.