Radiotherapy Fractionation: The Linear-Quadratic Model
Deliver a fractionated radiotherapy course to a 3D tumor and the healthy tissue around it, driven by the real linear-quadratic cell-survival model, and watch why splitting dose into small fractions spares normal tissue more than it spares the tumor.
This simulator renders a 3D tumor mass surrounded by a shell of healthy tissue and lets you deliver a real fractionated radiotherapy course to it. Every fraction is scored against the linear-quadratic cell-survival model — the same SF = exp(-(αd + βd²)) equation oncologists use to plan real treatment — with the tumor's higher α/β ratio and the normal tissue's lower one producing genuinely different survival curves as you change the dose per fraction and course length. Live readouts track surviving cell fraction, cumulative biologically effective dose (BED) for both tissues, and the therapeutic ratio between them, making visible the biological reason cancer treatment is split into many small doses instead of one large one.
Deliver a fractionated radiotherapy course to a 3D tumor and the healthy tissue around it, driven by the real linear-quadratic cell-survival model, and see why splitting dose into small fractions spares normal tissue more than it spares the tumor.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install