HomeMedicine & BiophysicsAntigenic Drift & Shift Simulator

Antigenic Drift & Shift Simulator

Interactive 3D model of influenza antigenic drift and shift: watch a viral population mutate through antigenic space, escape a neutralizing-antibody boundary generation by generation, and jump to a new subtype via reassortment.

Medicine & Biophysics3DModerate60 FPS📱 Mobile-adapted⇄ 2D version
medicine-topic-54 ↗ Open standalone

A 3D model of how influenza-like viruses evolve around the immune system. A viral population starts clustered on the vaccine strain at the centre of an abstract antigenic map, inside a translucent sphere marking the reach of neutralizing antibodies. Advance generations to watch point mutations (antigenic drift) push surviving virions outward under immune selection pressure, or trigger a reassortment event (antigenic shift) to see a subset jump straight to a new subtype outside the antibody boundary — with live readouts for generation count, mean antigenic distance, immune-escape fraction and population size.

⚙ Under the hood

Watch a 3D viral population mutate through antigenic space, escape a neutralizing-antibody boundary generation by generation (antigenic drift), or jump to a new subtype via a reassortment event (antigenic shift).

virologyimmunologyinfluenzaevolutionepidemiologyvaccines

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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