HomeMedicine & BiophysicsInterfragmentary Strain & Callus Differentiation

Interfragmentary Strain & Callus Differentiation

Interactive 3D simulator of Perren's interfragmentary strain theory: adjust fixation stiffness, axial load and gap size to watch a fracture callus differentiate into bone, cartilage or fibrous tissue as mechanical strain evolves.

Medicine & Biophysics3DModerate60 FPS📱 Mobile-adapted⇄ 2D version
bone-fracture-healing-callus-formation ↗ Open standalone

This simulator renders Perren's interfragmentary strain theory in 3D: a fractured long bone with an adjustable gap, stabilized by a chosen fixation method, under an adjustable axial load. Gap displacement and strain are computed from the combined stiffness of the fixation hardware and the growing callus, and a Gaussian mechanobiological growth window (peaking near moderate strain) determines how quickly — and into what tissue — the callus bridges the fracture, matching the clinical observation that rigid plating heals with minimal visible callus while flexible fixation produces a large external callus.

⚙ Under the hood

Explore Perren's interfragmentary strain theory in 3D: choose a fixation method and adjust load and gap size to see how mechanical strain at the fracture site determines whether the callus differentiates into bone, cartilage, or fibrous tissue.

orthopedicsbone healingbiomechanicsfracture fixationtissue differentiation

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install

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