Interfragmentary Strain & Callus Differentiation
Interactive 3D simulator of Perren's interfragmentary strain theory: adjust fixation stiffness, axial load and gap size to watch a fracture callus differentiate into bone, cartilage or fibrous tissue as mechanical strain evolves.
This simulator renders Perren's interfragmentary strain theory in 3D: a fractured long bone with an adjustable gap, stabilized by a chosen fixation method, under an adjustable axial load. Gap displacement and strain are computed from the combined stiffness of the fixation hardware and the growing callus, and a Gaussian mechanobiological growth window (peaking near moderate strain) determines how quickly — and into what tissue — the callus bridges the fracture, matching the clinical observation that rigid plating heals with minimal visible callus while flexible fixation produces a large external callus.
Explore Perren's interfragmentary strain theory in 3D: choose a fixation method and adjust load and gap size to see how mechanical strain at the fracture site determines whether the callus differentiates into bone, cartilage, or fibrous tissue.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install