MSC Paracrine Immunomodulation: Wound-Bed Diffusion Field (2D)

This is the 2D field companion to the 3D MSC paracrine simulator. Instead of a mean-field distance-sum evaluated at fixed macrophage positions, it solves a real diffusion–decay PDE for the secreted paracrine factor across a wound-bed cross-section, and adds continuous fresh-monocyte recruitment from the wound margins driven by inflammation severity — a dynamic the 3D fixed-population model has no equivalent for. Adjust MSC dose, secretion potency and factor diffusivity against a wound's ongoing inflammation severity to see whether the therapy's paracrine signal can outpace continued monocyte recruitment and tip the wound's tissue-repair trajectory toward healing.