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Reperfusion Injury Field 2D: Diffusion-Limited Reoxygenation

2D field simulation of transplant reperfusion injury: an oxygen reoxygenation front diffuses in from the vascular surface across a tissue cross-section, gating the xanthine-oxidase free-radical burst locally, with ROS spreading paracrine-style between neighboring tissue patches — the same reaction kinetics as the 3D sim, run on a genuine 2D reaction-diffusion grid.

Medicine & Biophysics2DAdvanced60 FPS📱 Mobile-adapted⇄ 3D version
2d-organ-transplantation ↗ Open standalone

This is the 2D companion to the 3D organ-transplant reperfusion sim: the same xanthine-oxidase free-radical kinetics, computed on a genuine 2D reaction-diffusion grid instead of a cloud of independently reperfused cells. Oxygen enters only at the vascular surface and must diffuse inward across the tissue cross-section before the free-radical burst can run at each patch, so a real reoxygenation front sweeps from the surface toward the avascular core — visibly slower and more damaging deep in the tissue, exactly the watershed-zone effect seen in real grafts. Reactive oxygen species also spread a short paracrine distance between neighboring patches. Tune cold ischemia time, antioxidant defense and the xanthine-oxidase inhibitor to see how they reshape both the reaction and how far the injury front reaches before it stalls.

⚙ Under the hood

2D field simulation of transplant reperfusion injury: an oxygen reoxygenation front diffuses in from the vascular surface across a tissue cross-section, gating the xanthine-oxidase free-radical burst locally, with ROS spreading paracrine-style between neighboring tissue patches — the same reaction kinetics as the 3D sim, run on a genuine 2D reaction-diffusion grid.

transplantischemia-reperfusionorgan preservationfree radicalsxanthine oxidasecell biology

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install

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