Sarcomere Cross-Bridge Kinetics (2D)
Interactive 2D sarcomere model driven by real Huxley (1957) two-state cross-bridge kinetics: stretch or compress the filament lattice, gate it with a Ca²⁺ Hill-equation activation curve, and impose a shortening velocity to watch length-tension and force-velocity curves emerge from the same numerically-integrated attachment/detachment ODE.
This 2D companion to the 3D myofibril model replaces its length-tension lookup table with a real, numerically-integrated kinetic engine: A.F. Huxley's 1957 two-state cross-bridge model, tracking a population of myosin heads across a range of elastic strain states and advancing their attachment/detachment probabilities with an operator-split ODE solver every frame. Sarcomere length still sets filament overlap, but overlap here is derived from filament geometry with two extra interference terms — double thin-filament overlap and Z-disc jamming — that a simple zone-intersection integral misses. A Ca²⁺ slider gates cross-bridge attachment through a cooperative Hill-equation activation curve, and a new shortening-velocity control lets the same kinetic engine reproduce Hill's classic hyperbolic force-velocity relationship, a dimension the 3D original does not model at all.
2D sarcomere model driven by real Huxley (1957) two-state cross-bridge kinetics, numerically integrated every frame: stretch or compress the filament lattice, gate attachment with a Ca2+ Hill-equation activation curve, and impose a shortening velocity to watch length-tension and Hill force-velocity curves emerge from the same ODE.
2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install