Chitosan Wound Dressing: 2D Electrostatic Flocculation Map

This 2D companion looks straight down onto a thin plane of wound fluid instead of into an orbiting 3D box. A population of chitosan chain segments and a population of negatively-charged cells interact through the same real screened-Coulomb (Yukawa) force as the 3D simulation, with the amine protonation fraction set by the Henderson–Hasselbalch equation and the electrostatic screening range set by the Debye length of the surrounding ionic strength. Drag the wound pH, degree of deacetylation, saline concentration and chitosan dose and watch the flocculation index respond exactly as the underlying chemistry predicts — dense aggregation at low pH and high deacetylation, and weak, diffuse clustering once the wound turns alkaline or the exudate is highly saline. Drag on the canvas to pan the view and scroll to zoom in on individual clusters.