Chitosan Hemostatic Flocculation Simulator
Interactive 3D simulation of how chitosan wound-dressing polymer stops bleeding: protonated amine groups on the chitosan chain electrostatically flocculate anionic red blood cells, with pH, deacetylation degree and ionic strength all tunable.
Chitosan-based wound dressings stop bleeding within seconds, independent of the body's own clotting cascade, because the biopolymer's amine groups protonate into a polycation that electrostatically pulls anionic red blood cells and bacteria together into a physical plug. This simulation renders that mechanism directly: a population of chitosan chain segments and a population of negatively-charged cells interact through a real screened-Coulomb (Yukawa) force, with the amine protonation fraction set by the Henderson–Hasselbalch equation and the electrostatic screening range set by the Debye length of the surrounding ionic strength. Drag the wound pH, degree of deacetylation, saline concentration and chitosan dose and watch the flocculation index respond exactly as the underlying chemistry predicts — dense aggregation at low pH and high deacetylation, and weak, diffuse clustering once the wound turns alkaline or the exudate is highly saline.
Simulate how the chitosan polymer in hemostatic wound dressings stops bleeding: protonated amine groups turn each chain into a polycation that electrostatically flocculates anionic red blood cells, with pH, deacetylation degree and ionic strength all tunable.
3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install