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Spaceflight Hypercalciuria & Kidney Stone Risk

Interactive 3D model of astronaut kidney-stone risk: microgravity bone resorption raises urinary calcium, and fluid intake, resistive exercise and potassium-citrate countermeasures set the calcium-oxalate supersaturation ratio that drives real crystal growth in the collecting duct.

Long-Duration Spaceflight Physiology3DAdvanced60 FPS

Losing bone mineral in microgravity does not stay in the skeleton — it passes through the kidneys. This simulator models the real chain from unloaded-bone resorption to urinary calcium excretion to calcium-oxalate supersaturation, the physiological pathway behind astronauts' elevated kidney-stone risk on long missions. Set mission duration, daily fluid intake and resistive-exercise adherence, toggle the potassium-citrate countermeasure, and watch a 3D renal tubule and a thinning femur respond: ion flow, supersaturation ratio and a growing calcium-oxalate crystal all update from the same closed-form model NASA-funded studies use to plan hydration and countermeasure protocols for Mars-length missions.

⚙ Under the hood

Interactive 3D model tracing microgravity bone resorption to elevated urinary calcium, calcium-oxalate supersaturation and real crystal growth in a renal tubule, with fluid intake, resistive exercise and potassium-citrate countermeasures as live controls.

space medicinekidney stonebone lossmicrogravityphysiologythree.js

3D · Three.js / WebGL renderer · 60 FPS target · runs fully client-side, no install