Copy Number Variant Read-Depth Detector

This simulator generates a synthetic whole-genome sequencing read-depth trace across a chromosome, with a few hidden deletion and duplication segments buried in realistic sequencing noise, and renders every genomic bin as a 3D bar whose height and color encode its smoothed log2 depth ratio. Adjust sequencing noise and the number of CNV events to change the underlying sample, then tune the detection algorithm's smoothing window and call threshold to see exactly how those choices trade sensitivity for precision against the ground-truth CNV placement — the same trade-off real bioinformatics pipelines (CBS, HMM-based CNV callers) navigate when turning raw coverage into a clinically actionable copy-number call.