Home▸Genetics & Evolution▸Biotechnology Synthetic Biology Simulation

Genetic Toggle Switch: Synthetic Biology Circuit

Build and flip a synthetic genetic toggle switch: two mutually-repressing genes engineered into a cell, driven by Hill-function ODEs, switched between its two stable states with IPTG and aTc inducer pulses.

Genetics & Evolution2DModerate60 FPS📱 Mobile-adapted

Design and test a genetic circuit built from scratch: two engineered promoters, each repressing the other's gene, wired into a single cell. This simulator runs the real bistable-switch ODEs behind the Gardner–Collins–Cantor toggle switch, rendering the cell as a translucent 3D volume filled with two populations of glowing reporter proteins — red LacI/RFP and green TetR/GFP — whose particle counts track the live concentrations. Fire an IPTG or aTc inducer pulse to flip the circuit between its two stable states, tune promoter strength and repressor cooperativity, and watch the population settle into whichever state now dominates — a genetic memory element, the same kind of switch used in engineered biosensors and biofuel-production strains.

⚙ Under the hood

This simulation allows you to design and test genetic circuits within a controlled environment, mimicking the core principles of synthetic biology. Explore how engineered biological systems can be built from scratch, offering solutions for diverse challenges like biofuel production or drug discovery.

Synthetic BiologyBiotechnology

2D · HTML5 Canvas 2D · 60 FPS target · runs fully client-side, no install